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These pens never contain B12, glycine, niacinamide, or any other additive that would change the color

In a pilot trial of NAD+ intravenous infusion in healthy adults, subjects receiving 750 mg of NAD+ over 6 hours reported no negative symptoms at all, and there were no vital sign abnormalities or serious laboratory derangements compared to placebo

You may have vitamin B12 deficiency because of pernicious anemia or other reasons, such as taking certain medications, having certain health conditions, or drinking heavily

Human Biology and Health

The duration of a B12 injections effects varies, but most people experience benefits for a few weeks to a few months